Seroprevalence of anti-SARS-CoV-2 antibodies in health care workers in a complex South Brazilian hospital

Beatriz Sanada Spiri, Regielly Caroline Raimundo Cognialli, Regiane Nogueira Spalanzani, Douglas Câmara de Oliveira, Diésica Suiane Ferreira, Camila de Oliveira Pereira, Ludmilla Louise Moreira Amadeu, Adriana de Fátima Gabriel, Lili Volochen Lopuch, Rodolfo Correa de Barros, Maurício Becher, Sonia Mara Raboni, Sérgio Monteiro de Almeida, Bárbara Maria Cavalli, Indianara Rotta, Luciane Aparecida Pereira, Francielli Brusco Moreira, Gislene Reche de Almeida Takahashi, Carolina Lumi Tanaka Dino, Lucas Bochnia-Bueno, Bernardo Montesanti Machado de Almeida, Gustavo Genelhoud, Gislaine Custodio, Marisol Dominguez Muro, Railson Henneberg, Meri Bordignon Nogueira

Resumo


Introduction: Health care workers (HCWs) are highly susceptible to SARS-CoV-2 infection because of the close contact care required by patients.

Methods: A cross-sectional study involving HCW was conducted. Serological tests (lateral flow immunochromatographic assays) were performed from June 22 to July 17, 2020.

Results: A total of 3,739 employees were tested, resulting in 10.2% positivity. The seroprevalence in the support group was 11.4% (71/624) and 7.3% (32/438) in the administrative group, with a higher seroprevalence among those who reported symptoms (64/469; 13.6%).

Conclusions: Seroprevalence of anti-SARS-CoV-2 was higher in employees with related symptoms in both the support group and in professionals working in nursing wards.

Keywords: COVID-19, SARS-CoV-2, healthcare workers, seroprevalence, immunoassay.


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