USE OF CARBAPENEMICS AND POLYMIXIN B IN THE GENERAL INTENSIVE CARE UNIT OF A PRIVATE HOSPITAL OF CURITIBA -PR

Resumo

Background and objectives: It is estimated that in the next few years strains infections will be responsible for thousands of deaths and even higher-cost with health services. Antimicrobials are among the most commonly prescribed drugs in hospitals, and it is estimated that at least 50% of these are unnecessary or incorrect. These drugs are known to be increasing the dissemination of mechanisms that cause resistance to antimicrobials, a problem that is increasing worldwide and depleting pharmacotherapeutic options for the treatment of infections. This study had the purpose of quantifying the use of Carbapenemicos and Polymyxins, in the ICU of a private hospital of Curitiba-PR in 2017, as well as evaluates its employability, comparing with internal guidelines and protocols for the proper use of these drugs. Methods: Data were collected from the infection control unit of the hospital, pharmacy and support laboratory. Clinical data were analyzed as well as protocols for the use of the studied drugs.Results: During the study period, 1.3% of the patients used at least one of the antimicrobials. Meropenem was the most used, followed by Ertapenem,  most often emplyed on April and December respectively.